Wednesday, September 28, 2011

Some Antidepressants From Blood Thinners May Pose a Risk for Patients With Heart Disease

Heart attack patients who take both choosy serotonin reuptake inhibitor antidepressants and antiplatelet drugs such as aspirin or Plavix cause a higher risk for bleeding than those who annihilate anti-clotting drugs not, a new study finds. Commonly prescribed SSRIs cover Zoloft, Prozac, Paxil, Lexapro and the buy Valium online.
Antiplatelet drugs arrest blood cells from sticking together and forming a blood clot. Sincerity attack patients are commonly prescribed antiplatelet group therapy to reduce their risk of another core attack. But there's an increased chance of bleeding, which increases coequal further when certain other drugs are bewitched at the same time.
 It so happens that uncountable heart attack patients be undergoing depression symptoms and are prescribed antidepressants, celebrated the researchers at McGill University in Montreal. "We're in any case concerned about how other medicine clout interact with the medicines we be aware are essential to heart health and betterment after heart attack," said Dr. Kirk Garratt, clinical pilot of interventional cardiovascular research at Lenox Hill Polyclinic in New York City.
"Although SSRIs are in use accustomed to in only a few cardiac patients, culture that SSRIs can increase jeopardy of bleeding complications could be suffering with important implications for how we care for patients after stents and other heartlessness procedures."
In the Canadian analysis, the researchers looked at more than 27,000 core attack patients, aged 50 and older, and create that patients taking aspirin or Plavix solitarily had a similar risk of bleeding. But alluring an SSRI antidepressant and aspirin increased the risk of bleeding by 42 percent, and fetching an SSRI with both aspirin and clopidogrel (dual antiplatelet treatment) increased the risk by 57 percent. Bleeding included gastrointestinal bleeding, hemorrhagic thrombosis or other bleeding that required hospitalization or occurred in the sanatorium during treatment.
The researchers also initiate that the risk of bleeding was deign in women and in patients who had angioplasty after their sensibility attack. The study appears Sept. 26 in the Canadian Medical Relationship Journal. "Ultimately, clinicians requirement weigh the benefits of SSRI treatment against the risk of bleeding in patients with outstanding depression following acute myocardial infarction," the researchers wrote in a weekly news release. They urged doctors to be vigilant when buy generic valium to nerve attack patients on antiplatelet psychoanalysis.